Fig. 5

SBM inhibits the IL-23/Th17 axis. A Volcano plot for T cells, genes in red represented genes upregulated by IMQ, and genes in blue were downregulated by SBM. B Dotplot for the expression of genes related to IL-23/Th17 axis in T cells and keratinocytes. C Immunofluorescence images staining for CD3E (green), E-cadherin (green), IL-23 (red), IL-17A (red), and DAPI (blue) of skin tissue, scale bar = 20 μm