Fig. 1

SYD alleviated the colonic inflammation in DSS-induced mice. A Experimental schedule. Changes of B weight, C colon length, and D the DAI scores during the experiment. DAI = weight-losing score + bloody stool score + stool shape score [15]; weight-losing score: 0 - no weight-losing, 1 - weight-losing between 1 and 5%, 2 - weight-losing between 5 and 10%, 3 - weight-losing between 10 and 15%, 4 - weight-losing more than 15%; blood stool score: 0 - no bloody stool, 2 - positive occult blood test without bloody stool in naked eye, 4 - blood stool in naked eye; stool shape score: 0 - normal shape, 2 - soft strip stool, 4 - loose stool. E Representative images of HE stained sections of the colon (20 × , 100 μm). F The concentrations of IL-1β, IL-2, IL-6, TNF-α and IFN-γ in the colonic tissue and the serum. Compared with NC, ^*P ≤ 0.05, ^**P ≤ 0.01; compared with M, ^#P ≤ 0.05, ^##P ≤ 0.01; compared with SYD-L, ^&P ≤ 0.05, ^&&P ≤ 0.01; compared with SYD-M, ^▲P ≤ 0.05, ^▲▲P ≤ 0.01; compared with SYD-H, ^●P ≤ 0.05, ^●●P ≤ 0.01