Fig. 3

SYD regulated the SCFAs metabolism from the intestinal flora. A Analysis of the bacterial diversity - Sobs index and Shannon index. B PCoA based on Bray-Curtis distance (Adonis: R² = 0.458, P = 0.000). C Relative abundances of the top 50 genera. D LEfSe analysis of the KEGG pathways based on the predicted 16S rDNA genes by PICRUSt algorithm (LDA score ≥ 2 and P ≤ 0.05). SYD both promoted SCFAs production in the E faeces and F serum. G Expression of the Gpr43 mRNA in the colonic tissues confirmed by RT-qPCR. H Expression of GPR43 determined by WB analysis and normalized to GAPDH. 3 mice per group. Compared with NC, ^*P ≤ 0.05, ^**P ≤ 0.01; compared with M, ^#P ≤ 0.05, ^##P ≤ 0.01