Fig. 2

Application of TCM diagnosis and GPCRs in the treatment of breast cancer. As the symptoms of breast cancer change, the composition or dosage of TCM changes. TCM products include bupleurum, poria, and white rhizoma. The FDA-approved anticancer drug motixafortide can regulate GPCRs (CXCR, STTR and GPR54) against BC. BC breast cancer, CXCR chemokine receptor, GPR54 G protein-coupled receptor 54, SSTR somatostatin receptor