Comprehensive biomarker analysis of metabolomics in different syndromes in traditional Chinese medical for prediabetes mellitus

Table 4 Comparison of the glycolipid-related indicators between the normal blood glucose group and PreDM group among the SRYP patients

	NDMSRYP n = 20 (Male: 9 Female: 11)	PDMSRYP n = 20 (Male: 12 Female: 8)	t / z	p
SBP (mmHg)	114.00 ± 13.24	120.20 ± 10.89	1.617	0.114	n.s
DBP (mmHg)	75.90 ± 10.18	78.40 ± 7.76	0.873	0.388	n.s
FBG (mmol/L)	5.35 ± 0.33	6.04 ± 0.55	4.811	0.001	***
2-h PG (mmol/L)	5.69 ± 1.13	9.12 ± 1.21	9.265	0.001	***
HbA1c (%)	4.83 ± 0.29	5.28 ± 0.63	2.902	0.006	**
FINS (μU/mL)	6.38 ± 4.49	9.87 ± 6.13	2.054	0.047	*
UA (mmol/L)	333.90 ± 100.23	353.57 ± 118.89	0.566	0.575	n.s
TG (mmol/L)	1.99 ± 1.80	1.96 ± 0.87	0.070	0.947	n.s
TC (mmol/L)	4.32 ± 0.71	4.96 ± 1.24	2.003	0.052	n.s
HDL-C (mmol/L)	1.25 ± 0.39	1.28 ± 0.37	0.250	0.804	n.s
LDL-C (mmol/L)	2.86 ± 0.69	3.23 ± 0.97	1.390	0.173	n.s
HOMA-IR	1.55 ± 1.14	1.69 ± 1.77	0.297	0.768	n.s
HOMA-IS	0.96 ± 0.56	0.57 ± 0.40	2.534	0.016	*
HOMA-β (%)	66.86 ± 40.66	79.25 ± 50.68	0.853	0.399	n.s

SBP systolic blood pressure, DBP diastolic blood pressure, FBG fasting blood glucose, 2-h PG 2-hour post-load blood glucose, HbA1c glycosylated hemoglobin, FINS fasting insulin, UA uric acid, TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, HOMA-IR homeostatic model assessment for insulin resistance, HOMA-IS homeostatic model assessment for insulin sensibility, HOMA-β homeostatic model assessment of β-cell function. n.s. not significant, *p < 0.05, **p < 0.01, ***p < 0.001. The Mann–Whitney U test was used to test for significant differences between the groups, data are n (%) or mean ± SD

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