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Fig. 5 | Chinese Medicine

Fig. 5

From: The improvement of modified Si-Miao granule on hepatic insulin resistance and glycogen synthesis in type 2 diabetes mellitus involves the inhibition of TNF-α/JNK1/IRS-2 pathway: network pharmacology, molecular docking, and experimental validation

Fig. 5

mSMG ameliorated hyperglycemia, hyperlipidemia, IR and serum TNF-α in KK-Ay mice. A Body weight. B Fasting blood glucose. C 2-h blood glucose of OGTT. D The area under the curve of OGTT. E HbA1c. F HOMA-IR. G Serum total cholesterol. H Serum triglyceride. I Serum low density lipoprotein cholesterol. J Serum tumor necrosis factor-α. K Alanine aminotransferase. L Aaspartate transaminase. M Serum creatinine. N Blood urea nitrogen. Data are expressed as mean ± SD (n = 6, *P < 0.05, **P < 0.01, ***P < 0.001)

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