Fig. 2

XFZYD modulates the metabolic profile of the cortex following TBI. A Illustration of cortical tissue using HE staining and Nissl staining. B Histograms illustrate the measurement of damaged neurons in the brain. n = 5. C The metabolomic profiles were clustered using PLS-DA. n = 10. D The validation plot of the PLS-DA model was generated from the cross-validation. E The Venn diagram shows that XFZYD governs 26 metabolites in the cortex. F GO biological processes functional enrichment analysis. G Chord diagram of the KEGG/GO pathways related to vessel and corresponding targets. ***p < 0.001