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Fig. 5 | Chinese Medicine

Fig. 5

From: Chlorogenic acid attenuates pyrrolizidine alkaloid-induced liver injury through modulation of the SIRT1/FXR signaling pathway

Fig. 5

Cga attenuates PA-induced liver injury by activating the SIRT1/FXR pathway. A The expression of the protein SIRT1 was measured by WB in mouse livers. Bar graphs show summary data (n = 3). B The mRNA level of Sirt1 was evaluated by qRT-PCR (n = 6). C The expression of the proteins Ac-Lys and FXR were measured by IP analysis in mouse livers (n = 3). Data are shown as the means ± SEM and analyzed by one-way ANOVA. ###P < 0.001 vs. Vehicle; ***P < 0.001 vs. TA

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