Fig. 1
From: Pharmacological effects of bile acids on polycystic ovary syndrome via the regulation of chemerin
A schematic representation of the animal experiment. This schematic diagram illustrates the experimental timeline and treatment groups for investigating the effects of various bile acids on PCOS rats. The study lasted 35Â days and was divided into two phases: an initial 21-day modelling phase with letrozole to induce PCOS, followed by a 14-day treatment phase with different therapeutic agents. This study assesses several endpoints, including body weight, ovarian and uterine weights, histopathological analysis of ovarian morphology, hormonal profiles (testosterone, estradiol, progesterone, luteinizing hormone, follicle-stimulating hormone, and their ratios), and chemerin protein isoforms