Fig. 4

SSS treatment increased tight junction protein expression in AIS mice after delayed tPA administration. A Western blotting of Tight junction proteins ZO-1, VIPR1, Occludin. B–D Quantification analysis of expressions of ZO-1 (B), VIPR1 (C), Occludin (D). E, F Representative images of immunofluorescent staining of ZO-1 (E) and Occludin (F). G–H Quantification analysis of expressions of ZO-1 (G) and Occludin (H). scale bar = 25 µm. ^*p < 0.05 vs MCAo, ^#p < 0.05 vs tPA