Fig. 1

CS-IVa ameliorates CCl₄-induced hepatic injury and hepatic fibrosis. A Liver histopathological alterations determined by H&E staining in mice induced with CCl₄ and treated with or without CS-IVa; Masson's trichome and Sirius Red staining were performed on liver tissues obtained from different experimental groups; scale bar = 100 µm, n = 3. B, C Masson's trichrome- and Sirius Red-positive areas. D, E Serum levels of ALT, AST and F liver hydroxyproline in CCl₄ treated mice, n = 6. The data are presented as the means ± SDs. ^##p < 0.01 vs. the control group; ^**p < 0.01 vs. the CCl₄ group