Fig. 2

CS-IVa ameliorated BDL-induced liver injury and hepatic fibrosis. A Liver histopathological alterations in H&E-stained sections obtained from mice subjected to BDL and treated with or without CS-IVa; Masson's trichome and Sirius Red staining were performed on liver tissues obtained from different groups; scale bar = 100 µm, n = 3. B, C Masson's trichrome- and Sirius Red-positive areas. D The liver index of the different groups. E–H Serum levels of ALT, AST, TBiL, DBiL and I liver hydroxyproline in BDL induced mice, n = 6. The data are presented as means ± SDs. ^##p < 0.01 vs. the control group; ^**p < 0.01 vs. the BDL group