Fig. 4

CS-IVa inhibited hepatic fibrosis induced by CCl4 through downregulating the YAP pathway. A CS-IVa treatment led to a significant decrease in the protein expression of YAP, TAZ, TEAD2, α-SMA and COL1A1 in liver tissues affected by CCl4. B The mRNA levels of YAP, TAZ, α-SMA and COL1A1 also downregulated by CS-IVa, n = 3. The data are presented as means ± SDs. ##p < 0.01 vs. the control group; **p < 0.01 vs. the CCl4 group