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Fig. 5 | Chinese Medicine

Fig. 5

From: Astragaloside IV accelerates hematopoietic reconstruction by improving the AMPK/PGC1α-mediated mitochondrial function in hematopoietic stem cells

Fig. 5

AS-IV enhances HSC mitochondrial function after radiation injury. A Flow cytometry was utilized to assess the proportion of c-kit+ HSC in the bone marrow of each group 10 days post-treatment; B Histograms showing the percentage of c-kit+ HSC in the bone marrow of each group; C Histograms showing the changes in mitochondrial membrane potential of c-kit+ HSC in the bone marrow of each group; D An ATP assay kit was used to detect the concentration of ATP produced by BM cells; E–K Targeted metabolomics analysis was utilized to analyze changes in the concentrations of citric acid, malic acid, fumaric acid, succinic acid, α-ketoglutaric acid, cis-aconitic acid, and oxaloacetic acid in bone marrow. Data represent the mean ± standard deviation of three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 compared with model

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Chinese Medicine

ISSN: 1749-8546

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