Fig. 2

HLJD decoction reduced the expression of Aβ42 and total tau in the HIP of 5xFAD mice. A ELISA analyses for Aβ42 levels in the HIP of mice (n = 3). B Representative images of ThS staining. Scale bars, 25 µm. C Quantification of B (n = 4). D Representative images of Aβ42 staining in the HIP. Scale bars, 25 µm. E Quantification of Aβ42 positive area (n = 4). F Representative images of tau in the HIP. Scale bars, 25 µm. G Quantification of tau positive area (n = 4). H Diagram of the Aβ plaques and total tau protein levels in the HIP of 5xFAD mice treated with or without HLJD decoction. Data are presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001