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Fig. 4 | Chinese Medicine

Fig. 4

From: Traditional Chinese medicine Youguiyin decoction ameliorate glucocorticoid-induced osteonecrosis in rat by modulating ROS/PHD2/HIF-1α oxidative stress signaling pathway in bone marrow mesenchymal stem cells

Fig. 4

The effects of YGY decoction on ROS, PHD2, HIF-1α, and osteogenic expression in GA-ONFH rats. A Oxidative stress levels in the femoral head of rats in all groups. B Oxidative stress levels in the serum of rats in all groups. C Immunohistochemical staining results of the femoral head in each group of rats. Scale bar: 200 µm. D Western blot results of the femoral head in each group of rats. E Quantitative analysis of immunohistochemical positive expression in each group of rats (n = 9 technical replicates, 3 fields/sample). F Quantitative analysis of expression of western blot in each group of rats (n = 3 independent experiments). Statistical analysis: Unpaired t-test. ##P < 0.01 and ###P < 0.001 vs Con group. nsP > 0.05,*P < 0.05, **P < 0.01 and ***P < 0.001 vs Mod group

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Chinese Medicine

ISSN: 1749-8546

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