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Correction: Total tanshinones ameliorates cGAS-STING-mediated inflammatory and autoimmune diseases by affecting STING-IRF3 binding
Chinese Medicine volume 19, Article number: 147 (2024)
Correction to: Chinese Medicine (2024) 19:107 https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13020-024-00980-4
Following publication of the original article [1], the authors reported that the vertical axis of Fig. 4D should be marked as "IFN-β", but it is mistakenly marked as "IL6". To ensure that readers receive accurate information, Fig. 4 has been updated and the authors declare that this correction does not affect the conclusion of the article.
The correct Fig. 4 has been provided in this Correction.
The incorrect Fig. 4 is:
TTN inhibits DMXAA-induced activation of STING downstream signalling in vivo. A–F C57BL/6 J mice were randomly divided into four groups (n = 6 per group). The administration group received the appropriate dose of tanshinone by gavage for 7 consecutive days, while the blank and DMXAA groups received equal amounts of excipients, and one hour after the last administration, the mice received an intraperitoneal injection of DMXAA (25 mg/kg), except for the blank group. Serum and peritoneal lavage fluid were taken after four hours. The levels of IFN-β, TNF-α and IL-6 in serum and peritoneal lavage fluid were determined by enzyme-linked immunosorbent assay (n = 6 per group). Data in (A–F) are presented as Mean ± SEM, one-way ANOVA followed by Dunnett’s post hoc test was used to detect statistical differences between the analyzed multiple groups. *p < 0.05, **p < 0.01 and ***p < 0.001 vs. the model group, NS, not significant
The correct Fig. 4 is:
TTN inhibits DMXAA-induced activation of STING downstream signalling in vivo. A–F C57BL/6 J mice were randomly divided into four groups (n = 6 per group). The administration group received the appropriate dose of tanshinone by gavage for 7 consecutive days, while the blank and DMXAA groups received equal amounts of excipients, and one hour after the last administration, the mice received an intraperitoneal injection of DMXAA (25 mg/kg), except for the blank group. Serum and peritoneal lavage fluid were taken after four hours. The levels of IFN-β, TNF-α and IL-6 in serum and peritoneal lavage fluid were determined by enzyme-linked immunosorbent assay (n = 6 per group). Data in (A–F) are presented as Mean ± SEM, one-way ANOVA followed by Dunnett’s post hoc test was used to detect statistical differences between the analyzed multiple groups. *p < 0.05, **p < 0.01 and ***p < 0.001 vs. the model group, NS, not significant
The original article [1] has been corrected.
Reference
Li C, Wen J, Zhan X, Shi W, Ye X, Yao Q, Chen S, Zheng C, Wang X, Wen X, Xiao X, Wang Y, Bai Z. Total tanshinones ameliorates cGAS-STING-mediated inflammatory and autoimmune diseases by affecting STING-IRF3 binding. Chin Med. 2024;19:107. https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13020-024-00980-4.
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Li, C., Wen, J., Zhan, X. et al. Correction: Total tanshinones ameliorates cGAS-STING-mediated inflammatory and autoimmune diseases by affecting STING-IRF3 binding. Chin Med 19, 147 (2024). https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13020-024-00996-w
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DOI: https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s13020-024-00996-w