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  1. Traditional Chinese medicine (TCM) is widely used in the management of chronic obstructive pulmonary disease (COPD). This study aimed to evaluate the clinical efficacy of comprehensive therapy based on TCM pat...

    Authors: Jiansheng Li, Yang Xie, Minghang Wang, Suyun Li, Xuefeng Yu, Nianzhi Zhang, Zhengang Zhu, Wei Zhang, Jihong Feng, Zikai Sun, Lin Lin, Zhijia Sun, Hailong Zhang and Xueqing Yu
    Citation: Chinese Medicine 2025 20:66
    Content type: Research Published on:

  2. Electroacupuncture (EA) is verified to modulate glycemic changes in T2DM, and this is partially related to sensory neurotransmitters. However, EA-mediated communication mechanism between them and acupoint spec...

    Authors: Yun Liu, Jiahui Xie, Zhi Yu, Meirong Gong, Qian Li, Guanhu Yang, Bin Xu and Tiancheng Xu
    Citation: Chinese Medicine 2025 20:65
    Content type: Research Published on:

  3. Rheumatoid arthritis (RA) with cold pattern is an important type of RA according to the theory of traditional Chinese medicine. Fuzi (also known as the lateral roots of Aconitum carmichaelii Debx.) represents a t...

    Authors: Juan Liu, Dandan Zhang, Yaochuan Zhou, Jinlu Wu, Wuwen Feng and Cheng Peng
    Citation: Chinese Medicine 2025 20:64
    Content type: Research Published on:

  4. Alcoholic liver disease (ALD), a consequence of excessive alcohol consumption, is characterized by high incidence and mortality rates. Presently, there are no effective pharmacological interventions available ...

    Authors: Sha Huang, Yuhua Wang, Jinjie Wen, Wenjuan Ji, Qiuxiang Zeng, Kaili Deng, Min Li, Shanshan Kuang, Wen Zhang, Mo Chan, Chuying Zhou, Zhiping Lv and Shaohui Huang
    Citation: Chinese Medicine 2025 20:63
    Content type: Research Published on:

  5. Mass spectrometry (MS)-based metabolomics has emerged as a transformative tool to unraveling components and their mechanisms in traditional Chinese medicine (TCM). The integration of advanced analytical platfo...

    Authors: Guang-Qin Liao, Hong-Mei Tang, Yuan-Di Yu, Li-Zhi Fu, Shuang-Jiao Li and Mai-Xun Zhu
    Citation: Chinese Medicine 2025 20:62
    Content type: Review Published on:

  6. To observe the effect of electro-acupuncture (EA) on cardiomyocytes ferroptosis induced by myocardial ischemia/reperfusion injury (MIRI) in mice and to investigate whether this effect occurs via the nuclear fa...

    Authors: Xiao Li, Yu-xin Sun, Adi Wirawan Tjahjono, Ying Wei, Xiang Li, Qian-hua Zheng, Wen-chuan Qi and Fan-rong Liang
    Citation: Chinese Medicine 2025 20:61
    Content type: Research Published on:

  7. Obesity has become a critical public health challenge worldwide. Prioritizing prevention and tackling root causes—rather than merely managing symptoms—is critical to curbing this pandemic. Strategies that acti...

    Authors: Zhiqi Huang, Ziyang Zhao, Haonan Shi, Runcheng He, Qianqian Feng, Yang Geng, Lei Zhang, Ti Zhang, Zhenteng Yan, Zhanhong Jia, Yanyan Jiang, Jianning Sun, Ang Cai, Shifen Dong and Lin Yang
    Citation: Chinese Medicine 2025 20:60
    Content type: Research Published on:

  8. Parkinson’s disease (PD) affects 1–2% of the global population and presents significant therapeutic challenges. Due to the limitations of existing treatments, there is a pressing need for alternative approache...

    Authors: Halin Jeon, Ju-Young Oh, Sora Ahn, Mijung Yeom, In Jin Ha, Hong-Seok Son, Seong-Eun Park, Juhan Park, Eugene Huh, In-Yeop Baek, Min-Ho Nam, Changsu Na, Myung Sook Oh and Hi-Joon Park
    Citation: Chinese Medicine 2025 20:59
    Content type: Research Published on:

  9. Scalp acupuncture is a promising potential therapy for neurological disorders. However, the development of its stimulation targets—both in identifying novel targets and refining the precision of their localiza...

    Authors: Yuefeng Wu, Qiao Kong, Yuanyuan Li, Yuan Feng, Binlong Zhang, Yu Liu, Siyi Yu, Jiao Liu, Jin Cao, Fangyuan Cui and Jian Kong
    Citation: Chinese Medicine 2025 20:58
    Content type: Research Published on:

  11. Dendrobium (DEN) have been utilized as valuable medicinal resource in China used for millennia for prevention and treatment of various diseases, particularly diabetes via alteration of their disordered gut microb...

    Authors: Junju Zou, Qianbo Song, David Tai Wai Lau, Pang Chui Shaw and Zhong Zuo
    Citation: Chinese Medicine 2025 20:56
    Content type: Research Published on:

  12. The incidence of osteonecrosis is increasing annually due to the widespread use of glucocorticoids. Recent evidence suggests a significant association between glucocorticoid-induced osteonecrosis and oxidative...

    Authors: Hongzhong Xi, Hao Chen, Jiahao Fu, Shuai He, Xin Liu, Guangquan Sun and Bin Du
    Citation: Chinese Medicine 2025 20:55
    Content type: Research Published on:

  13. Acupoint massage is a non-invasive traditional therapy that has demonstrated reliable clinical outcomes in pain management, mental health relief, sleep disorder regulation, gastrointestinal treatment, and as a...

    Authors: Chongjie Yao, Xinyu Zeng, Shuaipan Zhang, Bin Xiao, Pingping Sun, Lingjun Kong, Jiming Tao and Min Fang
    Citation: Chinese Medicine 2025 20:54
    Content type: Review Published on:

  14. Helicobacter infection, which is the leading cause of gastritis and stomach cancer, has become common worldwide. Almost all Helicobacter-infected patients have chronic active gastritis, also known as Helicobac...

    Authors: Danni Chen, Wenlai Wang, Xiangyun Chen, Ning Liang, Jiawang Li, Wei Ding, Hongrui Zhang, Zhen Yang, Hongxia Zhao and Zhenhong Liu
    Citation: Chinese Medicine 2025 20:53
    Content type: Review Published on:

  16. The therapeutic utility of Panax notoginseng saponins (Xuesaitong soft capsules) for patients with acute ischemic stroke (AIS) was previously demonstrated through the PANax notoginseng Saponins Treatment of aDult...

    Authors: Tingting Li, Anxin Wang, Xiaoli Zhang, Luda Feng, Peipei Du, Ying Gao, Xunming Ji, Haiqing Song and Chi Zhang
    Citation: Chinese Medicine 2025 20:51
    Content type: Research Published on:

  17. Alzheimer’s disease (AD) is a progressive neurodegenerative disorder predominantly affecting the elderly population. It is characterized by cognitive deficits associated with the accumulation of amyloid-beta p...

    Authors: Rui-Kang Pang, Jia Shi, Xiang-Yu Peng, Shan Su, Jia-Yi Zheng, Kai Le, Vincent W. Keng, Shi-Jie Zhang and Xiao-Xiao Li
    Citation: Chinese Medicine 2025 20:50
    Content type: Research Published on:

  18. Sepsis is a life-threatening infectious disease characterized by an uncontrolled inflammatory response and consequent multi-organ dysfunction. The kidneys, as primary excretory organs with high blood flow, are...

    Authors: Lei Wang, Zhong-Yao Li, Chong-Lei Zhong, Zi-Yang Teng, Bin Wang, Asma Rehman, Li-Wen Han, Ke-Wu Zeng, Ji-Guo Zhang and Zhi-Yuan Lu
    Citation: Chinese Medicine 2025 20:49
    Content type: Research Published on:

  19. The popularity of herbal formulas is increasing worldwide. Nevertheless, the effective compound is challenging to identify due to its intricate composition and multiple targets.

    Authors: Jiamu Ma, Peng Wei, Xiao Xu, Ruijuan Dong, Xixi Deng, Feng Zhang, Mengyu Sun, Mingxia Li, Wei Liu, Jianling Yao, Yu Cao, Letian Ying, Yuqing Yang, Yongqi Yang, Xiaopeng Wu and Gaimei She
    Citation: Chinese Medicine 2025 20:48
    Content type: Research Published on:

  20. Lignans derived from Schisandra chinensis have attracted significant attention for their diverse pharmacological activities and clinical potential. This review presents a comprehensive analysis of the pharmacolog...

    Authors: Danushiya Ehambarampillai and Murphy Lam Yim Wan
    Citation: Chinese Medicine 2025 20:47
    Content type: Review Published on:

  21. The appearance of DNA damage often involves the participation of related enzymes, which can affect the onset and development of various diseases. Several natural active compounds have been found to efficiently...

    Authors: Jiali Liang, Wanqing Liu, Tong Zhang, Dean Guo, Jiyu Gong and Zizhao Yang
    Citation: Chinese Medicine 2025 20:46
    Content type: Review Published on:

  22. Polycystic ovary syndrome (PCOS) poses significant health risks for women of reproductive age, and conventional treatments typically involve anti-hormonal interventions or surgical procedures, which often lead...

    Authors: Tian-Tian Tong, Long-Bo Bai, Lee-Fong Yau, Jiu-Yan Li, Hao Huang and Zhi-Hong Jiang
    Citation: Chinese Medicine 2025 20:45
    Content type: Research Published on:

  23. Radiotherapy can damage hematopoietic stem cells (HSC) in bone marrow, leading to impaired hematopoietic function. Current treatments mainly target differentiated hematopoietic progenitor cells, which may acce...

    Authors: Ling Zhang, Wanqi Xu, Yueying Zeng, Long Wang, Jiesi Luo, Xiaogang Zhou, Qibing Mei, Dalian Qin, Anguo Wu, Jianming Wu and Feihong Huang
    Citation: Chinese Medicine 2025 20:44
    Content type: Research Published on:

  24. With the development of new Chinese medicines and the need for clinical double-blind experiments, the use of placebos in Chinese medicine is becoming increasingly important. However, due to the diverse colors ...

    Authors: Tingting Teng, Jingze Zhang, Peiqi Miao, Lipeng Liang, Xinbo Song, Dailin Liu and Junhua Zhang
    Citation: Chinese Medicine 2025 20:43
    Content type: Research Published on:

  25. Gastric cancer (GC) is a common malignancy with poor prognosis and lack of efficient therapeutic methods. Shen Qing Weichang Formula (SQWCF) is a patented traditional herbal prescription for GC, but its effica...

    Authors: Yi Wang, Xiaoyu Sun, Mingming Ren, Fangqi Ma, Ruohan Zhao, Xiaohong Zhu, Yan Xu, Nida Cao, Yuanyuan Chen, Yongfu Pan and Aiguang Zhao
    Citation: Chinese Medicine 2025 20:42
    Content type: Research Published on:

  26. Obesity is frequently linked to chronic systamic inflammation and presents significant challenges to public health. Aurantio-obtusin (AO) boosted the brown adipose tissue (BAT) thermogenesis in diet-induced ob...

    Authors: Ruiyu Wu, Runping Liu, Ranyun Chen, Yijie Li, Xiaoyong Xue, Yinhao Zhang, Fanghong Li, Jiaorong Qu, Lingling Qin, Chen Wang and Xiaojiaoyang Li
    Citation: Chinese Medicine 2025 20:41
    Content type: Research Published on:

  27. In the past, the drug research and development has predominantly followed a "single target, single disease" model. However, clinical data show that single-target drugs are difficult to interfere with the compl...

    Authors: Yu Yuan, Lulu Yu, Chenghao Bi, Liping Huang, Buda Su, Jiaxuan Nie, Zhiying Dou, Shenshen Yang and Yubo Li
    Citation: Chinese Medicine 2025 20:40
    Content type: Review Published on:

  28. Classical prescriptions of Chinese medicine represent the crystallized wisdom of millennia of clinical practice, enduring as cornerstones of therapeutic intervention due to their demonstrated efficacy across g...

    Authors: Chang Liu, Pengwei Gao, Xiaoying Liu, Min Kuang, Haoran Xu, Yangming Wu, Wenjun Liu and Shengpeng Wang
    Citation: Chinese Medicine 2025 20:39
    Content type: Review Published on:

  29. Intravenous tissue plasminogen activator (tPA) is currently the only FDA-approved thrombolytic therapy for acute ischemic stroke (AIS), however, relative narrow therapeutic time window (within 4.5 h of AIS ons...

    Authors: Jiacheng Hu, Yiyang Li, Xingping Quan, Yan Han, Jinfen Chen, Mengchen Yuan, Ying Chen, Manfei Zhou, Enze Yu, Jiahao Zhou, Dawei Wang, Ruibing Wang and Yonghua Zhao
    Citation: Chinese Medicine 2025 20:38
    Content type: Research Published on:

  30. Epilepsy, one of the most common neurological diseases, affects more than 70 million people worldwide. Anti-seizure drugs targeting membrane ion channels or GABAergic neurotransmission are the first choices fo...

    Authors: Minjuan Sun, Xiaoyun Qiu, Zhijian Yuan, Cenglin Xu and Zhong Chen
    Citation: Chinese Medicine 2025 20:37
    Content type: Review Published on:

  31. Liver fibrosis is a representative scarring response that can ultimately lead to liver cancer. However, relevant antifibrotic drugs for the effective treatment of liver fibrosis in humans have not yet been ide...

    Authors: Kai Gao, Wei Zhang, Dong Xu, Meina Zhao, Xingru Tao, Yunyang Lu and Jingwen Wang
    Citation: Chinese Medicine 2025 20:36
    Content type: Research Published on:

  32. Castration-resistant prostate cancer (CRPC) has been a major cause of tumor-associated death among men worldwide. The discovery of novel therapeutic medicines for CRPC remains imperative. Atractylenolide I (AT...

    Authors: Chenglin Han, Bin Yang, Yuxuan Deng, Peng Hu, Bintao Hu, Xiaming Liu, Tao Wang, Chengbao Li, Jihong Liu and Huixing Yuan
    Citation: Chinese Medicine 2025 20:35
    Content type: Research Published on:

  33. Pyrrolizidine alkaloids (PAs), recognized globally for their hepatotoxic properties, significantly contribute to liver damage through an imbalance in bile acid homeostasis. Addressing this imbalance is crucial...

    Authors: Jie Xu, Qiongwen Xue, Aizhen Xiong, Yilin Chen, Xunjiang Wang, Xing Yan, Deqing Ruan, Yumeng Zhang, Zhengtao Wang, Lili Ding and Li Yang
    Citation: Chinese Medicine 2025 20:34
    Content type: Research Published on:

  34. Shi Zheng (SZ, syndrome of dampness) is a major syndrome type in traditional Chinese Medicine (TCM), the ambiguity of its pathomechanism and the lack of blood diagnostic indicators have limited the understanding ...

    Authors: Wenkai Wang, Le Yang, Wanhua Li, Ye Sun, Hui Sun, Yanjia Chen, Junling Ren, Jianwen Guo, Shuyun Wei, Fengye Lin, Guangli Yan, Ying Han, Qubo Chen and Xijun Wang
    Citation: Chinese Medicine 2025 20:33
    Content type: Research Published on:

  35. Fructus Viticis Total Flavonoids (FVTF) is a novel candidate preparation that possesses anticancer activity. However, the role and mechanism of FVTF-inhibiting human hepatocellular carcinoma (HCC) cell stem pr...

    Authors: Xiao-Cheng Cao, Jinwu Peng, Ye-Bei Qiu, Wei Zhu, Jian-Guo Cao, Hui Zou, Zheng-Zheng Yu, Di Wu, Shan-Shan Lu, Wei Huang, Hong Yi and Zhi-Qiang Xiao
    Citation: Chinese Medicine 2025 20:32
    Content type: Research Published on:

  36. Colorectal adenoma is a common precancerous lesion with a high risk of malignant transformation. Traditional Chinese medicine and its complex prescriptions have shown promising efficacy in the treatment of ade...

    Authors: Limei Gu, Yinuo Ma, Shunji Liu, Qinchang Zhang, Qiang Zhang, Ping Ma, Dongfang Huang, Haibo Cheng, Yang Sun and Tingsheng Ling
    Citation: Chinese Medicine 2025 20:31
    Content type: Research Published on:

  37. Electroacupuncture (EA) is commonly used for pain control in clinical practice, yet the precise mechanisms underlying its action are not fully understood. The rostral ventromedial medulla (RVM) plays a crucial...

    Authors: Kexing Wan, Qian Xu, Yulong Shi, Chi Cui, Jie Lei, Kailing Zhang, Qingxu Yao, Yiqing Rao, Ziyu Zhou, Yisong Wu, Jiale Mei, Hui-Lin Pan, Xianghong Jing, He Zhu and Man Li
    Citation: Chinese Medicine 2025 20:30
    Content type: Research Published on:

  38. Acupuncture as a representative treatment method of traditional Chinese medicine, has been found to have a significant effect on mild to moderate depression without obvious side effects, but the mechanism thro...

    Authors: Jianfu Ma, Xuan Yin, Kaiyu Cui, Jiqing Wang, Wei Li and Shifen Xu
    Citation: Chinese Medicine 2025 20:29
    Content type: Review Published on:

  39. Acute gout arthritis (AGA) is a common metabolic joint disease and urgently needs a safer alternative therapy due to the significant side effects from long-term use of primary medications. Folium Hibisci Mutabili...

    Authors: Yichen Zhao, Jiahui Zhang, Wei Yan, Ping Jiang, Juncheng Li, Haojun He, Honghong Ma, Yuxin Zhang, Kai Yang, Min Jiang and Xiaobing Xi
    Citation: Chinese Medicine 2025 20:28
    Content type: Research Published on:

  40. Salidroside is a potential therapeutic agent for myocardial infarction (MI), exerting therapeutic effects on macrophage migration inhibitory factor (MIF)-regulated mitochondrial quality control. Our aim was to...

    Authors: Baiyang You, Jie Zhang, Chuyan Yang, Yaoshan Dun, Dake Qi, Yuqiong Long, Jing Cheng, Yuan Lin, Nanjiang Zhou, Tanghao Zeng, Jie Dong and Suixin Liu
    Citation: Chinese Medicine 2025 20:27
    Content type: Research Published on:

  41. Those minor, even trace natural products sometimes exhibit exciting activities and possess unique structures; however, it is challenging to pursue and identify such components using routine LC−MS/MS platforms ...

    Authors: Huixia Huo, Hang Zhang, Huiting Liu, Jiale Ma, Qian Zhang, Yunfang Zhao, Jiao Zheng, Pengfei Tu, Yuelin Song and Jun Li
    Citation: Chinese Medicine 2025 20:26
    Content type: Research Published on:

  42. Hepatocellular carcinoma (HCC) poses ongoing difficulties for public health systems due to its high incidence and poor prognosis. Huqi formula (HQF), a well-known prescription in traditional Chinese medicine, ...

    Authors: Donghao Yin, Xiang Li, Xuemeng Yang, Xiaofei Shang, Zhen Li, Jiahao Geng, Yanyu Xu, Zijing Xu, Zixuan Wang, Zimeng Shang, Zhiyun Yang, Linlan Hu, Quanwei Li, Jiabo Wang, Xinhua Song, Xiuhui Li…
    Citation: Chinese Medicine 2025 20:25
    Content type: Research Published on:

  44. Breast cancer (BC) is a prevalent form of cancer among women. Despite the emergence of numerous therapies over the past few decades, few have achieved the ideal therapeutic effect due to the heterogeneity of B...

    Authors: Shensuo Li, Lijun Zhang, Wen Zhang, Hongyu Chen, Mei Hong, Jianhua Xia, Weidong Zhang, Xin Luan, Guangyong Zheng and Dong Lu
    Citation: Chinese Medicine 2025 20:23
    Content type: Research Published on:

  45. In the past few years, the emergence of organoids and organ-on-a-chip (OOAC) technologies, which are complementary to animal models and two-dimensional cell culture methods and can better simulate the internal...

    Authors: Jiayue Yang, Yu Jiang, Mingxing Li, Ke Wu, Shulin Wei, Yueshui Zhao, Jing Shen, Fukuan Du, Yu Chen, Shuai Deng, Zhangang Xiao, Wen Yuan and Xu Wu
    Citation: Chinese Medicine 2025 20:22
    Content type: Review Published on:

  46. Aconitum tanguticum (Maxim.) Stapf (ATS) is a rare Tibetan medicinal plant that belongs to the Ranunculaceae family. This herb is mainly distributed in the high-altitude areas of Qinghai, Gansu provinces, and Tib...

    Authors: Xiang Meng, Yu-Peng Liu, Jia-Wei Dai, Yuan Bai, Xin Hu, Muhammad Azhar and Xian-Ju Huang
    Citation: Chinese Medicine 2025 20:21
    Content type: Research Published on:

  47. Authors: Jingyuan Zhang, Siyun Yang, Xiaodong Chen, Fanqin Zhang, Siyu Guo, Chao Wu, Tieshan Wang, Haojia Wang, Shan Lu, Chuanqi Qiao, Xiaoguang Sheng, Shuqi Liu, Xiaomeng Zhang, Hua Luo, Qinglin Li and Jiarui Wu
    Citation: Chinese Medicine 2025 20:20
    Content type: Correction Published on:

    The original article was published in Chinese Medicine 2025 20:2

  48. Sepsis-induced acute lung injury (SALI) is characterized by a dysregulated inflammatory and immune response. As a key component of the innate immune system, macrophages play a vital role in SALI, in which a ma...

    Authors: Yake Li, Sinan Ai, Yuan Li, Wangyu Ye, Rui Li, Xiaolong Xu and Qingquan Liu
    Citation: Chinese Medicine 2025 20:19
    Content type: Review Published on:

  49. Polycystic ovary syndrome (PCOS) is a complex neuroendocrine disorder characterized by dysregulation of the hypothalamus. Both electroacupuncture (EA) and manual acupuncture (MA) have demonstrated therapeutic ...

    Authors: Yu Wang, Yicong Wang, Yuning Chen, Wenhan Lu, Xiaoyu Tong, Jiajia Li, Wenhao Gao, Rui Huang, Wei Hu and Yi Feng
    Citation: Chinese Medicine 2025 20:18
    Content type: Research Published on:

  50. Steroid-resistant asthma (SRA) is a form of asthma resistant to corticosteroid therapy, which is characterized by the presence of neutrophil-predominant inflammatory response and neutrophil extracellular traps...

    Authors: Xu Wang, Hui-Ming Peng, Meng-Ru Zhang, Jing-Jing Li, Chuan-Peng Zhao, Ya-Li Zhang, Si-Yu Wang, Si-Ying Zhu, Jian-Kang Lu, Hai-Long Yin, Qiang Yin and Jin-Bo Fang
    Citation: Chinese Medicine 2025 20:17
    Content type: Research Published on:
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Chinese Medicine

ISSN: 1749-8546

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